Premature Ejaculation – Causes

Magnesium in Human Semen: Possible Role in Premature Ejaculation
Although magnesium is involved in many biological processes, and it is found in higher levels in semen than serum, its role in human semen has not been elucidated. This investigation was conducted to evaluate the relationship between premature ejaculation and the levels of seminal magnesium.  The levels of magnesium, zinc, copper, and selenium were evaluated with an atomic absorption spectrophotometer in serum and seminal plasma in 3 groups of men: (a) normal sperm parameters (15) (b) oligoasthenozoospermia (15), and genuine premature ejaculation (9). There were normal serum and semen levels of all the elements in the three groups, but significantly lower seminal plasma magnesium levels in men with premature ejaculation. The hormonal profile and body mass index (BMI) had no association with premature ejaculation. Decreased levels of magnesium give rise to vasoconstriction from increased thromboxane level, increased endothelial intracellular Ca2+, and decreased nitric oxide. This may lead to premature emission and ejaculation processes. Magnesium is probably involved in semen transport. More research into the role of magnesium in the male physiology of reproductive tract, especially its association with premature ejaculation, is advocated.
Omu, A. E., et al. Magnesium in human semen: possible role in premature ejaculation. Arch Androl. 46(1):59-66, 2001.

Yohimbine, Erectile Capacity, and Sexual Response in Men

Men with premature ejaculation problems who were administered 30 mg of yohimbine per day were found to have better control over their climax, and yohimbine also slightly postponed ejaculation.

Rowland, D. L., et al. Yohimbine, erectile capacity, and sexual response in men. Archives of Sexual Behavior 26:49-62, 1997.

These substances can cause premature ejaculation:

  • Hormones
  • Excessive levels of Prolactin
  • Neurotransmitters
  • Excessive Histamine
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